product summary
request information :
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-CCL8 / MCP-2
catalog :
LS-C42983
quantity :
price :
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
western blot, ELISA
more info or order :
LifeSpan Biosciences product webpage
product information
?AntibodyID :
42721
AntibodyName :
LS-C42983
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
Anti-CCL8 / MCP-2
Specificity :
Specific for human MCP-2 (Monocyte Chemoattractant Protein 2), otherwise known as CCL8, a 76 amino acid CC chemokine originally isolated from the human osteosarcoma cell line MG-63, which is expressed at highest levels in peripheral blood cells and the small intestine. MCP-2 acts as a chemoattractant for monocytes, lymphocytes, eosinophils and basophils, due to its ability to bind to the common MCP receptor, chemokine (C-C motif) receptor 2 (CCR2), and also CCR1 and CCR3. Proteolytic cleavage of MCP-2 into the NH2-terminally truncated form, MCP-2 (6-76), results in the loss of chemotactic activity, forming a functional C-C chemokine inhibitor, which may be important during inflammatory responses
ClonalityDesc :
Polyclonal
AntigenModification :
N-Terminus
PresentationDesc :
Lyophilized, PBS, pH 7.4.
ImmunogenDesc :
Recombinant human MCP-2.
PurificationDesc :
Purified
ResuspensionLiquidDesc :
Distilled Water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add azide.
IsotypeName :
IgG
Gene :
CCL8 / MCP-2
StandardGeneSymbol :
CCL8
gene family :
Intercrine
Subfamily :
Intercrine beta
Reactivity :
Human
Usage :
ELISA (0.5 µg/ml), Func (12 - 16 µg/ml), WB (0.1 - 0.2 µg/ml)
Synonyms :
CCL8, C-C motif chemokine 8, HC14, MCP2, Monocyte chemotactic protein 2, Scya10, SCYA8, Small-inducible cytokine A8, MCP-2, Chemokine (C-C motif) ligand 8
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.