product summary
request information :
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-CCL2 / MCP-1
catalog :
LS-C42981
quantity :
price :
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
immunohistochemistry - paraffin section, western blot, ELISA
more info or order :
LifeSpan Biosciences product webpage
product information
?AntibodyID :
42719
AntibodyName :
LS-C42981
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
Anti-CCL2 / MCP-1
Specificity :
Specific for human MCP-1 (Monocyte Chemoattractant Protein 1), otherwise known as CCL2, a 76 amino acid CC chemokine which acts as a chemoattractant for monocytes, basophils, activated T cells and NK cells, through binding with the seven-transmembrane G protein-coupled receptor, CCR2. The recruitment of mononuclear cells by MCP-1, has established this chemokine as an important factor in innate immunity, implicated in the pathogenesis of inflammatory diseases such as rheumatoid arthritis, multiple sclerosis, uveitis and bronchial asthma. Increasing studies have also linked MCP-1 with the polarization of activated T cells into the T helper 2 (Th2) subset, revealing a role for MCP-1 in the adaptive immune response
ClonalityDesc :
Polyclonal
PresentationDesc :
Lyophilized, PBS, pH 7.4.
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant human MCP-1.
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
+4°C or -20°C, Avoid repeated freezing and thawing.
ResuspensionLiquidDesc :
Distilled Water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add azide.
IsotypeName :
IgG
Gene :
CCL2 / MCP-1
StandardGeneSymbol :
CCL2
gene family :
Intercrine
Subfamily :
Intercrine beta
Reactivity :
Human
Usage :
ELISA (0.5 µg/ml), IHC-P, WB (0.1 - 0.2 µg/ml)
Synonyms :
CCL2, C-C motif chemokine 2, Chemokine (C-C motif) ligand 2, GDCF-2, HC11, HSMCR30, MCP1, SCYA2, Small-inducible cytokine A2, Monocyte secretory protein JE, MCAF, MCP-1, Monocyte chemotactic protein 1, SMC-CF
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.