product summary
request information :
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-IGF-II / IGF2
catalog :
LS-C42967
quantity :
price :
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
immunohistochemistry - paraffin section, western blot, ELISA
more info or order :
LifeSpan Biosciences product webpage
product information
?AntibodyID :
42705
AntibodyName :
LS-C42967
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
Anti-IGF-II / IGF2
Specificity :
Specific for human IGF-II (Insulin-like Growth Factor II), a 67 amino acid mitogenic polypeptide and member of the Insulin gene family, synthesized by various fetal tissues during prenatal development, under the influence of placental lactogen. IGF-II is a growth factor Exhibits both paracrine and autocrine properties and signals by binding to the type 1 and type 2 insulin-like growth factor receptors (type 1 IGFR and type 2 IGFR), and also to the insulin receptor (IR). The availability of IGF-II is dependent upon its attachment to, and release from, various IGF binding proteins (IGFBPs), a relationship which has been investigated in breast cancer research
ClonalityDesc :
Polyclonal
PresentationDesc :
Lyophilized, PBS, pH 7.4.
ImmunogenDesc :
Recombinant human IGF-II.
PurificationDesc :
Purified
RecommendedStorageDesc :
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
ResuspensionLiquidDesc :
Restore with 0.1 ml of deionized water
IsotypeName :
IgG
Gene :
IGF-II / IGF2
StandardGeneSymbol :
IGF2
gene family :
Hormone
Reactivity :
Human
Usage :
ELISA (0.5 - 2 µg/ml), Func (3.1 - 4.6 µg/ml), IHC-P, WB (0.1 - 0.2 µg/ml)
UsageText :
ELISA: LS-C42967 may be used in an indirect ELISA or as a capture reagent in a sandwich ELISA with LS-C42968 as the detection reagent. Western Blot: LS-C42967 may used under either reducing or non-reducing conditions.
Synonyms :
IGF2, C11orf43, Insulin-like growth factor II, IGF-II, PP9974, Somatomedin-A
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.