This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
MAPT / Tau Antibody (aa1-16, Serum) LS-C42946
catalog :
LS-C42946
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry - paraffin section
product information
AntibodyID :
42684
AntibodyName :
LS-C42946
TargetSpecies :
Human
Host Species :
Goat
Product Name :
MAPT / Tau Antibody (aa1-16, Serum) LS-C42946
Specificity :
Recognizes the N-terminal region of human Microtubule-associated protein tau, also known as tau, Neurofibrillary tangle protein or Paired helical filament-tau. Tau is a a ~50-70 kD heterogeneous group of proteins that are involved in microtubule assembly. In healthy brain tissue tau is localized to the axons of neurons. Tau has been associated with some neurological disease states including Alzheimer's disease where it localizes to neurofibrillary tangles. Several isoforms of human tau can be generated by alternative splicing,is expected to recognize all isoforms with the possible exception of isoform-3 which demonstrates multiple residue changes within the region of the immunizing peptide.
ClonalityDesc :
Polyclonal
AntibodyModification :
Serum Unconjugated
AntigenModification :
aa1-16
PresentationDesc :
0.1% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide MAEPRQEFEVMEDHAG corresponding to amino acids 1-16 of human Tau. (AA 1-16). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla (100%); Gibbon, Monkey, Green monkey, Baboon, Dog, Horse (94%); Marmoset, Goat, Elephant, Bovine, Rabbit (88%); Mouse, Rat, Prairie vole (81%).
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG
Gene :
MAPT / Tau
StandardGeneSymbol :
MAPT
Reactivity :
Human
Usage :
IHC-P (1:50 - 1:100), WB (1:1000)
ShortWebDescription :
Tau antibody LS-C42946 is an unconjugated goat polyclonal antibody to human Tau (MAPT ). Validated for IHC and WB.
UsageText :
Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin embedded sections. Sodium buffer pH6.0 is recommended for this purpose.
Synonyms :
MAPT, FTDP-17, MSTD, Neurofibrillary tangle protein, PHF-tau, MTBT2, PPND, DDPAC, MAPTL, MTBT1, Paired helical filament-tau, TAU
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.