This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-CASP3 / Caspase 3 Antibody LS-C42792
catalog :
LS-C42792
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry - paraffin section
product information
AntibodyID :
42530
AntibodyName :
LS-C42792
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
Anti-CASP3 / Caspase 3 Antibody LS-C42792
Specificity :
Recognizes the Caspase-3 cell death protease, also known as CPP32, YAMA and apopain. Caspase-3 is a ~32 kD protein, activated during apoptosis by cleavage into 17 kD and 11 kD fragments. Recognizes both intact Caspase-3 and the 17 kD fragment, but not the 11 kD fragment. In immunohistochemical studies Caspase-3 expression has been shown to be widespread, but not present in all cell types. Differences in the level of Caspase-3 have been reported in cells of short-lived nature (e. g. germinal centre B cells) and those that are long lived (e. g. mantle zone B cells).
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
Serum, 0.09% sodium azide.
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant human caspase-3.
IsotypeName :
IgG
Gene :
CASP3 / Caspase 3
StandardGeneSymbol :
CASP3
gene family :
Protease
Subfamily :
Cysteine C14
Reactivity :
Human
Usage :
IHC-P (1:100 - 1:500), WB (1:1000)
UsageText :
Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.
Synonyms :
CASP3, Apopain, CASP-3, Caspase-3, CPP32B, CPP32, Cysteine protease CPP32, SCA-1, SREBP cleavage activity 1, Yama, Procaspase3, Caspase 3, CPP-32, PARP cleavage protease, Protein Yama
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.