This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-BAX Antibody (aa43-61) LS-C42785
catalog :
LS-C42785
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunoprecipitation, immunohistochemistry - paraffin section
product information
AntibodyID :
42523
AntibodyName :
LS-C42785
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
Anti-BAX Antibody (aa43-61) LS-C42785
Specificity :
Recognizes the human BAX protein, a proapoptotic member of the Bcl-2 family. BAX accelerates programmed cell death by binding to and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. It also induces the release of cytochrome C, activation of CASP3 and thereby apoptosis. Defects in BAX are found in some cell lines from hematopoietic malignancies as T-cell acute lymphoblastic leukemia, Burkitt lymphoma, and plasmacytoma. BAX migrates as a 21kD band in western blotting applications.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa43-61
PresentationDesc :
Serum, 0.09% sodium azide.
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide corresponding to amino acids 43-61 of human Bax.
IsotypeName :
IgG
Gene :
BAX
StandardGeneSymbol :
BAX
gene family :
Apoptosis
Reactivity :
Human
NonReactiveSpecies :
Mouse
Usage :
IHC-P (1:1000 - 1:2000), IP (1:1000), WB
UsageText :
Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Western Blot: LS-C42785 recognizes a 21 kD band in western blotting using cell lysates from either normal breast tissue or MCF-7 cells.
Synonyms :
BAX, BCL2-associated X protein, Bcl2-L-4, Apoptosis regulator BAX, Bcl-2-like protein 4, BCL2L4
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.