product summary
request information :
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-CX3CL1 / Fractalkine
catalog :
LS-C42779
quantity :
price :
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
western blot, ELISA
more info or order :
LifeSpan Biosciences product webpage
product information
?AntibodyID :
42517
AntibodyName :
LS-C42779
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
Anti-CX3CL1 / Fractalkine
Specificity :
Specific for human fractalkine, otherwise known as CX3CL1, a 397 amino acid CX3C chemokine which signals through the CX3CR1 receptor and is expressed by various tissues including the brain, testis, lung, heart, kidney, colon and skeletal muscle. Adhesion of fractalkine to the CX3CR1 receptor triggers the chemotaxis and adhesion of leucocytes, including T cells, monocytes and NK cells and studies have suggested that fractalkine is involved in the regulation of brain microglia during neuroinflammatory processes (1) and may play a role in dendritic cell-mediated host defense against invading pathogens such as Legionella pneumophila
ClonalityDesc :
Polyclonal
PresentationDesc :
Lyophilized, PBS, pH 7.4.
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant human fractalkine.
PurificationDesc :
Purified
ResuspensionLiquidDesc :
Distilled Water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add azide.
IsotypeName :
IgG
Gene :
CX3CL1 / Fractalkine
StandardGeneSymbol :
CX3CL1
gene family :
Intercrine
Subfamily :
Intercrine delta
Reactivity :
Human
Usage :
ELISA (0.5 µg/ml), WB (0.1 - 0.2 µg/ml)
Synonyms :
CX3CL1, ABCD-3, C-X3-C motif chemokine 1, C3Xkine, Chemokine ntt, CXC3C, FKN, Fractalkine, Neurotactin, CXC3, NTN, SCYD1, Small-inducible cytokine D1
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.