This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
RAD9A / RAD9 Antibody (aa1125-1139) LS-C42615
catalog :
LS-C42615
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA
product information
AntibodyID :
42353
AntibodyName :
LS-C42615
TargetSpecies :
Yeast
Host Species :
Rabbit
Product Name :
RAD9A / RAD9 Antibody (aa1125-1139) LS-C42615
Specificity :
Detects Saccharomyces cerevisiae Rad9, a protein involved in the DNA damage checkpoint. In S. cerevisiae this checkpoint is mainly controlled by the PI(3) kinase-like kinase (PIKK) Mec1, which is activated in response to DNA damage. Activated Mec1 hyperphosphorylates Rad9, which in turn triggers the binding of Rad53, the ortholog of mammalian Chk2. Activated Rad53 specifically targets substrates required for cell cycle arrest, gene expression and efficient DNA repair. Mutations affecting Rad9 impair checkpoint induced cell-cycle arrest and increase genomic instability. Is pan reactive with both the phosphorylated and non-phosphorylated forms of this protein.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa1125-1139
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenType :
Synthetic peptide - KLH conjugated
ImmunogenDesc :
Synthetic peptide corresponding to aa 1125-1139 of yeast Rad9 protein conjugated to Keyhole Limpet Hemocyanin (KLH).
PurificationDesc :
Purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG
Gene :
RAD9A / RAD9
StandardGeneSymbol :
RAD9A
Reactivity :
Yeast
Usage :
ELISA (1:2000 - 1:4000), WB (1:50 - 1:250)
ShortWebDescription :
RAD9 antibody LS-C42615 is an unconjugated rabbit polyclonal antibody to yeast RAD9 (RAD9A) (aa1125-1139). Validated for ELISA and WB.
UsageText :
Western Blot: LS-C42615 detects a band of approximately 60kD.
Synonyms :
RAD9A, HRAD9, RAD9, RAD9 homolog, RAD9 (S. pombe) homolog, RAD9 homolog A (S. pombe)
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.