This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
TLR3 Antibody (C-Terminus) LS-C42338
catalog :
LS-C42338
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry - frozen section
product information
AntibodyID :
42076
AntibodyName :
LS-C42338
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
TLR3 Antibody (C-Terminus) LS-C42338
Specificity :
Recognizes human CD283, otherwise known as toll receptor 3, a 103.8 kD member of the evolutionarily conserved toll-like receptor family (TLRs), expressed at high levels in the placenta and pancreas and also expressed by dendritic cells. TLRs play an important role in the recognition of invading microbial pathogens during innate immunity, acting through adaptor molecules such as MyD88 and TRAF6. CD283 acts via a cytokine signaling pathway to induce the activation of NF-kappaB and type I interferons, and has been shown to recognize double-stranded viral RNA, including that of the Influenza A and West Nile virus. Has been shown as suitable for use in IHC on EL4 cytospins at 1 ug/ml.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
C-Terminus
PresentationDesc :
PBS, 0.02% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide corresponding to a 15 amino acid sequence located near human CD283 C-Terminus
PurificationDesc :
Purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG
Gene :
TLR3
StandardGeneSymbol :
TLR3
gene family :
Toll-like Receptor
Reactivity :
Human
Usage :
IHC-Fr, WB (1 - 2 µg/ml)
ShortWebDescription :
TLR3 antibody LS-C42338 is an unconjugated rabbit polyclonal antibody to human TLR3 (C-Terminus). Validated for IHC and WB.
UsageText :
Western Blot: LS-C42338 detects a band of approximately 103.8kD in human Daudi cell lysates.
Synonyms :
TLR3, CD283, Toll-like receptor 3, CD283 antigen, IIAE2
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.