This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
HP / Haptoglobin Antibody LS-C42319
catalog :
LS-C42319
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human
application :
immunocytochemistry
product information
AntibodyID :
42057
AntibodyName :
LS-C42319
TargetSpecies :
Human
Host Species :
Sheep
Product Name :
HP / Haptoglobin Antibody LS-C42319
Specificity :
Recognizes human haptoglobulin, a plasma protein that has high affinity for hemoglobin and is responsible for its capture and hepatic recycling. This process also acts to prevent kidney damage where hemoglobin would otherwise accumulate prior to excretion in the urine. Haptoglobin/hemoglobin complexes are cleared from the circulation in the liver by Kuppfer cells expressing the CD163 scavanger receptor. Two isoforms of human haptoglobin produced by alternative splicing have been described.(AHP082) binds to the canonical isoform 1 of human haptoglobin, binding to the truncated (missing residues 38-96) isoform 2 has not been evaluated. Mutation of the HP gene can lead to the development of Anhaptoglobinemia, a disease characterized by an absence of serum haptoglobin.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
GBS, 1 mM EDTA, 0.1% EACA, 0.09% Sodium Azide, 0.01% Benzamidine
ImmunogenType :
Purified protein
ImmunogenDesc :
Human haptoglobulin purified from serum.
PurificationDesc :
Ion exchange chromatography
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG
Gene :
HP / Haptoglobin
StandardGeneSymbol :
HP
Reactivity :
Human
NonReactiveSpecies :
Chicken, Bovine, Guinea pig
Usage :
ID (1:1), IF
ShortWebDescription :
Haptoglobin antibody LS-C42319 is an unconjugated sheep polyclonal antibody to human Haptoglobin (HP). Validated for ID and IF.
Synonyms :
HP, Binding peptide, Haptoglobin alpha(1S)-beta, Haptoglobin, beta polypeptide, Haptoglobin, Haptoglobin alpha(2FS)-beta, Haptoglobin, alpha polypeptide, HP2ALPHA2, BP, Zonulin, HPA1S
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.