This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
TAC1 / Substance P Antibody LS-C42165
catalog :
LS-C42165
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, pig
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 1
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; pig; 1:1000
Kaleczyc J, Podlasz P, Winnicka A, Wasowicz W, Sienkiewicz W, Zmudzki J, et al. Characterization of autonomic nerve markers and lymphocyte subsets in the ileal Peyer's patch of pigs infected experimentally with Brachyspira hyodysenteriae. J Comp Pathol. 2010;143:248-57 pubmed publisher
product information
AntibodyName :
LS-C42165
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
TAC1 / Substance P Antibody LS-C42165
Specificity :
Recognizes human Protachykinin-1, also known as PPT. Protachykinin-1 is a 129 amino acid ~15kD tachychinin involved in the excitation of neurons. Protachykinin-1 can be cleaved into a number of chains including substance P, neurokinin A, neuropeptide K, neuropeptide gamma and c-terminal flanking peptide. Recognizes an epitope within the substance P region of the molecule. There are potentially four isoforms of Protachykinin-1 (alpha - delta) formed by alternative splicing, all containing the substance P peptide region. Stains substance P secreting cells of the external median eminence of the hypothalamus and specific cells of the GI tract. Also stains neuronal structures.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenDesc :
Synthetic substance P conjugated to Keyhole limpet hemocyanin.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG
Gene :
TAC1 / Substance P
StandardGeneSymbol :
TAC1
gene family :
Hormone
Reactivity :
Chicken, Mouse, Human
Usage :
IF, IHC, IHC-Fr (1:50 - 1:200), IHC-P (1:50 - 1:200)
ShortWebDescription :
Substance P antibody LS-C42165 is an unconjugated rabbit polyclonal antibody to Substance P (TAC1) from human, mouse and chicken. Validated for IF and IHC. Cited in 1 publication.
UsageText :
Immunohistology: 0.01 M Sodium Citrate buffer, pH6.0 is recommended for this purpose.
Synonyms :
TAC1, Hs.2563, Neurokinin 1, Neurokinin 2, Neuromedin L, Neuropeptide K, NK2, NPK, Protachykinin beta, Protachykinin-1, Substance K, Substance P, Tachykinin, precursor 1, Neurokinin A, Neuropeptide gamma, PPT, Neurokinin alpha, NKA, NKNA, TAC2, Tachykinin 2
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.