product summary
request information :
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Anti-MMP14 / MMP-14
catalog :
LS-C42032
quantity :
price :
clonality :
polyclonal
host :
rabbit
reactivity :
human
application :
western blot, ELISA
more info or order :
LifeSpan Biosciences product webpage
product information
?AntibodyID :
41770
AntibodyName :
LS-C42032
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
Anti-MMP14 / MMP-14
Specificity :
Recognizes MMP14, also known as MT1-MMP, a metalloproteinase involved in the cleavage of type 1 collagen fibres at the cell surface, requiring homodimerization of MMP-14 via the hemopexin domain. MMP14 is the only membrane anchored collagenase. Besides cleaving collagens types I, II and III, MMP14 also degrades a range of extracellular macromolecules including aggrecan, vitronectin, fibronectin and laminins 1 and 5
ClonalityDesc :
Polyclonal
PresentationDesc :
PBS, 0.01% Thimerosal.
ImmunogenType :
Synthetic peptide - KLH conjugated
ImmunogenDesc :
Synthetic peptide derived from the hinge region between the catalytic and hemopexin domain of MMP-14 conjugated to KLH.
PurificationDesc :
Immunoaffinity purified
IsotypeName :
IgG
Gene :
MMP14 / MMP-14
StandardGeneSymbol :
MMP14
gene family :
Protease
Subfamily :
Metallopeptidase M10A
Reactivity :
Human
Usage :
ELISA, WB (1:1000 - 1:4000)
Synonyms :
MMP14, Membrane type-1 MMP, MT1-MMP, MT1MMP, MT-MMP, MT-MMP 1, Matrix metalloproteinase-14, MMP-14, MMP-X1, MTMMP1
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.