This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
LF / LTF / Lactoferrin Antibody (HRP) LS-C41996
catalog :
LS-C41996
clonality :
polyclonal
host :
domestic sheep
conjugate :
HRP
reactivity :
human
application :
immunohistochemistry - paraffin section, immunohistochemistry - frozen section
product information
AntibodyID :
41734
AntibodyName :
LS-C41996
TargetSpecies :
Human
Host Species :
Sheep
Product Name :
LF / LTF / Lactoferrin Antibody (HRP) LS-C41996
Specificity :
Recognizes human lactoferrin (LTF), an 80kD non-heme, iron-binding globular glycoprotein and member of the transferrin family present in milk and mucosal secretions, and also released from neutrophil granules during inflammation. LTF acts as a major first line defense against microbial infections, partly due to its ability to efficiently bind to and hence remove Fe3+ from the environment, but studies have also shown that LTF possesses bactericidal properties and proteolytic activity, capable of cleaving arginine-rich sequences within microbial proteins. Three isoforms of LTF have been identified: LTF-alpha, LTF-beta and LTF-gamma and receptors for LTF are expressed in the gastrointestinal tract, by macrophages, lymphocytes, neutrophils and platelets and also by some bacteria.
ClonalityDesc :
Polyclonal
AntibodyModification :
HRP
PresentationDesc :
PBS, 0.01% Thimerosal
ImmunogenDesc :
Lactoferrin purified from milk.
PurificationDesc :
Purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG
Gene :
LF / LTF / Lactoferrin
StandardGeneSymbol :
LTF
Reactivity :
Human
Usage :
ELISA (1:50), IHC-Fr, IHC-P
ShortWebDescription :
Lactoferrin antibody LS-C41996 is an HRP-conjugated sheep polyclonal antibody to human Lactoferrin (LF / LTF). Validated for ELISA and IHC.
UsageText :
Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Synonyms :
LTF, GIG12, Growth-inhibiting protein 12, HLF2, Lactotransferrin, Lactoferrin, LF, Neutrophil lactoferrin, Talalactoferrin
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.