product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
CSF2 / GM-CSF Antibody (clone 3209 (30-4)) LS-C41956
catalog :
LS-C41956
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3209 (30-4)
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, neutralization, immunohistochemistry - frozen section
citations: 1
Reference
van Helvoort E, Eijkelkamp N, Lafeber F, Mastbergen S. Expression of granulocyte macrophage-colony stimulating factor and its receptor in the synovium of osteoarthritis patients is negatively correlated with pain. Rheumatology (Oxford). 2020;59:3452-3457 pubmed publisher
product information
AntibodyID :
41694
AntibodyName :
LS-C41956
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
CSF2 / GM-CSF Antibody (clone 3209 (30-4)) LS-C41956
Specificity :
Recognizes recombinant and native human granulocyte macrophage colony stimulating factor (GM-CSF). Human Granulocyte colony stimulating factor (GM-CSF) is a 14.6kD glycoprotein, which is produced by T cells, macrophages, fibroblasts and endothelial cells. GM-CSF is involved in the stimulation of proliferation and differentiation of granulocyte and macrophage progenitor cells. The neutralization dose (ND50) of this batch, as determined by the proliferation of TF-1 cells, is approximately 0.3-0.5 Âug/ml in the presence of 0.5 ng/ml of recombinant human GM-CSF. The ND50 may vary depending on conditions.
ClonalityDesc :
Monoclonal
CloneName :
3209 (30-4)
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, 1% Trehalose
ImmunogenType :
Recombinant protein
ImmunogenDesc :
R-DNA
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
IsotypeName :
IgG1
Gene :
CSF2 / GM-CSF
StandardGeneSymbol :
CSF2
Reactivity :
Human
Usage :
ELISA (0.5 - 1 µg/ml), IHC, IHC-Fr (25 µg/ml), Neut, WB (1 - 2 µg/ml)
ShortWebDescription :
GM-CSF antibody LS-C41956 is an unconjugated mouse monoclonal antibody to human GM-CSF (CSF2). Validated for ELISA, IHC, Neut and WB. Cited in 1 publication.
UsageText :
Western Blot: LS-C41956 should be used under non-reducing conditions, reducing conditions are not recommended.
Synonyms :
CSF2, Colony-stimulating factor, CSF, GM-CSF, Molgramostin, GMCSF
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.