This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
GRIA1 / GLUR1 Antibody (C-Terminus) LS-C41927
catalog :
LS-C41927
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot, immunoprecipitation, immunohistochemistry - frozen section
product information
AntibodyID :
41665
AntibodyName :
LS-C41927
TargetSpecies :
Rat
Host Species :
Rabbit
Product Name :
GRIA1 / GLUR1 Antibody (C-Terminus) LS-C41927
Specificity :
Recognizes the glutamate receptor 1 (also known as AMPA) which acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. Linked to immobilized Protein A immunoprecipitates detergent-solubilized receptor from brain or transfected cells.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
C-Terminus
PresentationDesc :
PBS, 0.09% Sodium Azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
Synthetic peptide corresponding to the C-Terminus of the native molecule conjugated to Bovine Serum Albumin.
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
ResuspensionLiquidDesc :
Reconstitute with distilled water.
IsotypeName :
IgG
Gene :
GRIA1 / GLUR1
StandardGeneSymbol :
GRIA1
gene family :
Ion channel
Subfamily :
Glutamate receptor - ionotropic (NMDA receptor)
Reactivity :
Rat
Usage :
IHC-Fr (1 - 3 µg/ml), IP, WB (0.5 - 2.5 µg/ml)
ShortWebDescription :
GLUR1 antibody LS-C41927 is an unconjugated rabbit polyclonal antibody to rat GLUR1 (GRIA1) (C-Terminus). Validated for IHC, IP and WB.
UsageText :
Immunohistology: Paraformaldehyde or paraformaldehyde/glutaraldehyde are suitable. Cryostat and vibratome sections can be used with or without Triton X-100 treatment.
Synonyms :
GRIA1, AMPA 1, GluR-K1, HBGR1, GLUH1, GLUR1, GLURA, Glutamate receptor 1, GluR-A, GluA1, GluR-1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.