This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Complement C5 Antibody LS-C41851
catalog :
LS-C41851
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry - paraffin section
product information
AntibodyID :
41589
AntibodyName :
LS-C41851
TargetSpecies :
Human
Host Species :
Sheep
Product Name :
Complement C5 Antibody LS-C41851
Specificity :
Recognizes complement component 5 (C5), a member of the complement system. The complement system consists of a tightly regulated network of proteins. Its activation leads to a sequential cascade of enzymatic reactions, resulting in opsonisation of the pathogens and their removal by phagocytes, as well as cell lysis. Three pathways have been described, the antibody-dependent pathway (classical pathway), the alternative pathway and the lectin activation pathway. The complement system plays a critical role in both innate and adaptive immune responses. It is also involved in tissue regeneration, tumor growth and some human pathologies. Complement component 5 is the initiator of the effector terminal phase of the complement system. C5 convertase cleaves C5 into C5a, a potent anaphylatoxin, and C5b, ultimately resulting in the formation of the multimeric membrane attack complex (MAC) together with the other components of the terminal pathway (C5b-C9). Gives a single arc when tested by immunoelectrophoresis (IEP) against human plasma. The identity has been confirmed by double diffusion against fresh human plasma and a known anti human C5.
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
GBS, 1 mM EDTA, 0.1% EACA, 0.09% Sodium Azide, 0.01% Benzamidine
ImmunogenDesc :
Human C5, purified from plasma.
PurificationDesc :
Ion exchange chromatography
RecommendedStorageDesc :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze/thaw cycles.
IsotypeName :
IgG
Gene :
Complement C5
StandardGeneSymbol :
C5
Reactivity :
Human
Usage :
ID, IHC-P (1:100)
ShortWebDescription :
Complement C5 antibody LS-C41851 is an unconjugated sheep polyclonal antibody to human Complement C5. Validated for ID and IHC.
Synonyms :
C5, Anaphylatoxin C5a analog, CPAMD4, Complement C5, Complement component 5
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.