ITGA6/Integrin Alpha 6/CD49f Antibody (clone GoH3) LS-C41344 | LifeSpan Biosciences LS-C41344 product information

product summary

company name :

LifeSpan Biosciences

product type :

antibody

product name :

ITGA6/Integrin Alpha 6/CD49f Antibody (clone GoH3) LS-C41344

catalog :

LS-C41344

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

GoH3

reactivity :

human

application :

immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

more info or order :

LifeSpan Biosciences product webpage

citations: 7

Reference
Lai K, Yamashita S, Vitkus S, Shyr C, Yeh S, Chang C. Suppressed prostate epithelial development with impaired branching morphogenesis in mice lacking stromal fibromuscular androgen receptor. Mol Endocrinol. 2012;26:52-66 pubmed publisher
Grange C, Tapparo M, Collino F, Vitillo L, Damasco C, Deregibus M, et al. Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche. Cancer Res. 2011;71:5346-56 pubmed publisher
Jo M, Eastman B, Webb D, Stoletov K, Klemke R, Gonias S. Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. Cancer Res. 2010;70:8948-58 pubmed publisher
Xu T, Xu Y, Liao C, Lau R, Goldkorn A. Reprogramming murine telomerase rapidly inhibits the growth of mouse cancer cells in vitro and in vivo. Mol Cancer Ther. 2010;9:438-49 pubmed publisher
Nardella C, Carracedo A, Alimonti A, Hobbs R, Clohessy J, Chen Z, et al. Differential requirement of mTOR in postmitotic tissues and tumorigenesis. Sci Signal. 2009;2:ra2 pubmed publisher
Horwitz K, Dye W, Harrell J, Kabos P, Sartorius C. Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts. Proc Natl Acad Sci U S A. 2008;105:5774-9 pubmed publisher
Stepp M, Liu Y, Pal Ghosh S, Jurjus R, Tadvalkar G, Sekaran A, et al. Reduced migration, altered matrix and enhanced TGFbeta1 signaling are signatures of mouse keratinocytes lacking Sdc1. J Cell Sci. 2007;120:2851-63 pubmed

image

image 1 :

Human peripheral blood lymphocytes stained with purified GoH3, followed by anti-rat IgGs FITC

image 2 :

MDA-MB-231 breast cancer cells were stained with anti-CD49f (clone GoH3) followed by DyLight 649 Goat anti-rat Ig secondary antibody (red), plus DAPI staining for nuclei (blue). Images were taken under 20x bin4 (Filter set: EX647/10x, Dichroic 665LP, EM 700/70x) at exposure 4s. Data provided by Er Liu and John Nolan, La Jolla Institute for Bioengineering.

product information

AntibodyID :

41046

AntibodyName :

LS-C41344

TargetSpecies :

Human

Host Species :

Rat

Product Name :

ITGA6/Integrin Alpha 6/CD49f Antibody (clone GoH3) LS-C41344

Specificity :

ITGA6/CD49f from mouse and human

ClonalityDesc :

Monoclonal

CloneName :

GoH3

AntibodyModification :

Unconjugated

PresentationDesc :

Phosphate-buffered solution, pH 7.2, 0.09% sodium azide.

ImmunogenType :

Cells

ImmunogenDesc :

Cells

PurificationDesc :

Affinity purified

RecommendedStorageDesc :

Store at 4°C. Store undiluted.

IsotypeName :

IgG2a

Gene :

ITGA6/Integrin Alpha 6/CD49f

StandardGeneSymbol :

ITGA6

gene family :

Integrin

Reactivity :

Mouse, Human

Usage :

Flo, IHC, IHC-Fr, IP

UsageNotRecommended :

IHC-P

ShortWebDescription :

CD49f antibody LS-C41344 is an unconjugated rat monoclonal antibody to CD49f (ITGA6 / Integrin Alpha 6) from human. It is reactive with human and mouse. Validated for Flow, IHC and IP. Cited in 7 publications.

Synonyms :

ITGA6, CD49f, CD49f antigen, Integrin alpha6B, Integrin, alpha 6, Integrin alpha-6 precursor, VLA-6, Integrin alpha-6, ITGA6B

SalesRegion :

Worldwide

more info or order :

LifeSpan Biosciences product webpage

company information

LifeSpan Biosciences

2401 Fourth Avenue, Suite 900
Seattle, WA 98121

CustomerSupport@lsbio.com

https://www.lsbio.com

1-206-464-1554

headquarters: USA

Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.