product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
TNFRSF10A / DR4 Antibody (Extracellular Domain, clone DJR1) LS-C40989
catalog :
LS-C40989
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
DJR1
reactivity :
human
application :
flow cytometry
more info or order :
LifeSpan Biosciences product webpage
citations: 2
Reference
Chen K, Chen H, Tai W, Feng W, Hsu C, Chen P, et al. Activation of phosphatidylinositol 3-kinase/Akt signaling pathway mediates acquired resistance to sorafenib in hepatocellular carcinoma cells. J Pharmacol Exp Ther. 2011;337:155-61 pubmed publisher
Lundqvist A, Abrams S, Schrump D, Alvarez G, Suffredini D, Berg M, et al. Bortezomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: a novel method to potentiate natural killer cell tumor cytotoxicity. Cancer Res. 2006;66:7317-25 pubmed
image
image 1 :
LifeSpan Biosciences LS-C40989 image 1
Human DR4 transfected cells stained with purified DJR1, followed by anti-mouse IgG FITC
product information
AntibodyID :
40691
AntibodyName :
LS-C40989
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
TNFRSF10A / DR4 Antibody (Extracellular Domain, clone DJR1) LS-C40989
Specificity :
Extracellular domain of DR4-human IgG1 Fc fusion protein
ClonalityDesc :
Monoclonal
CloneName :
DJR1
AntibodyModification :
Unconjugated
AntigenModification :
Extracellular Domain
PresentationDesc :
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide.
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant human TNFRSF10A / DR4.
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C.
IsotypeName :
IgG1
Gene :
TNFRSF10A / DR4
StandardGeneSymbol :
TNFRSF10A
gene family :
TNF Receptor
Reactivity :
Human
Usage :
Flo
ShortWebDescription :
DR4 antibody LS-C40989 is an unconjugated mouse monoclonal antibody to human DR4 (TNFRSF10A) (Extracellular Domain). Validated for Flow. Cited in 2 publications.
Synonyms :
TNFRSF10A, APO2, CD261, DR4, TRAIL-R1, TRAILR-1, TRAILR1, TRAIL receptor 1, CD261 antigen, Cytotoxic TRAIL receptor, Death receptor 4
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.