product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
ITGA4 / VLA-4 / CD49d Antibody (clone 9F10) LS-C40971
catalog :
LS-C40971
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
9F10
reactivity :
human
application :
immunohistochemistry, flow cytometry, immunohistochemistry - frozen section
citations: 3
Reference
Mattapallil M, Silver P, Mattapallil J, Horai R, Karabekian Z, McDowell J, et al. Uveitis-associated epitopes of retinal antigens are pathogenic in the humanized mouse model of uveitis and identify autoaggressive T cells. J Immunol. 2011;187:1977-85 pubmed publisher
Palacios F, Moreno P, Morande P, Abreu C, Correa A, Porro V, et al. High expression of AID and active class switch recombination might account for a more aggressive disease in unmutated CLL patients: link with an activated microenvironment in CLL disease. Blood. 2010;115:4488-96 pubmed publisher
Kleinewietfeld M, Starke M, Di Mitri D, Borsellino G, Battistini L, Rotzschke O, et al. CD49d provides access to "untouched" human Foxp3+ Treg free of contaminating effector cells. Blood. 2009;113:827-36 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-C40971 image 1
Human peripheral blood lymphocytes stained with purified 9F10, followed by anti-mouse IgGs FITC
product information
AntibodyID :
40673
AntibodyName :
LS-C40971
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
ITGA4 / VLA-4 / CD49d Antibody (clone 9F10) LS-C40971
ClonalityDesc :
Monoclonal
CloneName :
9F10
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.2, 0.09% Sodium Azide
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C. Avoid freezing.
IsotypeName :
IgG1
Gene :
ITGA4 / VLA-4 / CD49d
StandardGeneSymbol :
ITGA4
gene family :
Integrin
Reactivity :
Dog, Sheep, Bovine, Cat, Horse, Human, Monkey, Baboon
Usage :
Flo, IHC, IHC-Fr
UsageNotRecommended :
IHC-P
ShortWebDescription :
CD49d antibody LS-C40971 is an unconjugated mouse monoclonal antibody to CD49d (ITGA4 / VLA-4) from human. It is reactive with human, baboon, bovine and other species. Validated for Flow and IHC. Cited in 3 publications.
Synonyms :
ITGA4, 269C wild type, CD49D, IA4, Integrin alpha-4, Integrin alpha 4, Integrin alpha-4 subunit, Integrin alpha-IV, VLA-4, VLA-4 subunit alpha, CD49d antigen
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.