product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
TLR2 Antibody (clone TL2.1) LS-C40823
catalog :
LS-C40823
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
TL2.1
reactivity :
human
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry
more info or order :
LifeSpan Biosciences product webpage
citations: 6
Reference
Nguyen K, Macaubas C, Truong P, Wang N, Hou T, Yoon T, et al. Serum amyloid A induces mitogenic signals in regulatory T cells via monocyte activation. Mol Immunol. 2014;59:172-9 pubmed publisher
Elass Rochard E, Rombouts Y, Coddeville B, Maes E, Blervaque R, Hot D, et al. Structural determination and Toll-like receptor 2-dependent proinflammatory activity of dimycolyl-diarabino-glycerol from Mycobacterium marinum. J Biol Chem. 2012;287:34432-44 pubmed publisher
Harris K. Monocytes differentiated with GM-CSF and IL-15 initiate Th17 and Th1 responses that are contact-dependent and mediated by IL-15. J Leukoc Biol. 2011;90:727-34 pubmed publisher
Weiss D, Souza C, Evanson O, Sanders M, Rutherford M. Bovine monocyte TLR2 receptors differentially regulate the intracellular fate of Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium. J Leukoc Biol. 2008;83:48-55 pubmed
Goo S, Han Y, Kim W, Lee K, Park S. Vibrio vulnificus IlpA-induced cytokine production is mediated by Toll-like receptor 2. J Biol Chem. 2007;282:27647-58 pubmed
Chavakis E, Hain A, Vinci M, Carmona G, Bianchi M, Vajkoczy P, et al. High-mobility group box 1 activates integrin-dependent homing of endothelial progenitor cells. Circ Res. 2007;100:204-12 pubmed
image
image 1 :
LifeSpan Biosciences LS-C40823 image 1
Human peripheral blood monocytes stained with TL2.1 FITC.
product information
AntibodyID :
40525
AntibodyName :
LS-C40823
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
TLR2 Antibody (clone TL2.1) LS-C40823
Specificity :
Human TLR2-transfected CHO cells
ClonalityDesc :
Monoclonal
CloneName :
TL2.1
AntibodyModification :
Unconjugated
PresentationDesc :
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide.
ImmunogenType :
Cells
ImmunogenDesc :
Cells
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG2a
Gene :
TLR2
StandardGeneSymbol :
TLR2
gene family :
Toll-like Receptor
Reactivity :
Human
Usage :
Flo, IHC, IP, WB
UsageNotRecommended :
IHC-P
ShortWebDescription :
TLR2 antibody LS-C40823 is an unconjugated mouse monoclonal antibody to human TLR2. Validated for Flow, IHC, IP and WB. Cited in 5 publications.
Synonyms :
TLR2, CD282 antigen, CD282, TIL4, Toll-like receptor 2
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.