product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
ITGAM / CD11b Antibody (clone CBRM1/5) LS-C40808
catalog :
LS-C40808
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CBRM1/5
reactivity :
human
application :
immunoprecipitation, flow cytometry
citations: 7
Reference
Kamp V, Pillay J, Lammers J, Pickkers P, Ulfman L, Koenderman L. Human suppressive neutrophils CD16bright/CD62Ldim exhibit decreased adhesion. J Leukoc Biol. 2012;92:1011-20 pubmed publisher
Curran C, Bertics P. Human eosinophils express RAGE, produce RAGE ligands, exhibit PKC-delta phosphorylation and enhanced viability in response to the RAGE ligand, S100B. Int Immunol. 2011;23:713-28 pubmed publisher
Theodoridis A, Eich C, Figdor C, Steinkasserer A. Infection of dendritic cells with herpes simplex virus type 1 induces rapid degradation of CYTIP, thereby modulating adhesion and migration. Blood. 2011;118:107-15 pubmed publisher
Cavnar P, Berthier E, Beebe D, Huttenlocher A. Hax1 regulates neutrophil adhesion and motility through RhoA. J Cell Biol. 2011;193:465-73 pubmed publisher
Wilson R, Winter S, Spees A, Winter M, Nishimori J, Sanchez J, et al. The Vi capsular polysaccharide prevents complement receptor 3-mediated clearance of Salmonella enterica serotype Typhi. Infect Immun. 2011;79:830-7 pubmed publisher
Pillay J, Ramakers B, Kamp V, Loi A, Lam S, Hietbrink F, et al. Functional heterogeneity and differential priming of circulating neutrophils in human experimental endotoxemia. J Leukoc Biol. 2010;88:211-20 pubmed publisher
Barthel S, Jarjour N, Mosher D, Johansson M. Dissection of the hyperadhesive phenotype of airway eosinophils in asthma. Am J Respir Cell Mol Biol. 2006;35:378-86 pubmed
image
image 1 :
LifeSpan Biosciences LS-C40808 image 1
PMA activated human granulocytes stained with CBRM1/5 FITC
product information
AntibodyID :
40510
AntibodyName :
LS-C40808
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
ITGAM / CD11b Antibody (clone CBRM1/5) LS-C40808
ClonalityDesc :
Monoclonal
CloneName :
CBRM1/5
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.2, 0.09% Sodium Azide
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C. Do not freeze.
IsotypeName :
IgG1
Gene :
ITGAM / CD11b
StandardGeneSymbol :
ITGAM
gene family :
Integrin
Reactivity :
Human
Usage :
Flo, IP
ShortWebDescription :
CD11b antibody LS-C40808 is an unconjugated mouse monoclonal antibody to human CD11b (ITGAM). Validated for Flow and IP. Cited in 7 publications.
Synonyms :
ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.