product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
PDCD1 / CD279 / PD-1 Antibody (clone EH12.2H7) LS-C40800
catalog :
LS-C40800
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
EH12.2H7
reactivity :
human
application :
flow cytometry
more info or order :
LifeSpan Biosciences product webpage
citations: 7
Reference
Conrad J, Ramalingam R, Smith R, Barnett L, Lorey S, Wei J, et al. Dominant clonotypes within HIV-specific T cell responses are programmed death-1high and CD127low and display reduced variant cross-reactivity. J Immunol. 2011;186:6871-85 pubmed publisher
Monteiro P, Gosselin A, Wacleche V, El Far M, Said E, Kared H, et al. Memory CCR6+CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin ?7. J Immunol. 2011;186:4618-30 pubmed publisher
Radziewicz H, Ibegbu C, Hon H, Bedard N, Bruneau J, Workowski K, et al. Transient CD86 expression on hepatitis C virus-specific CD8+ T cells in acute infection is linked to sufficient IL-2 signaling. J Immunol. 2010;184:2410-22 pubmed publisher
Vojnov L, Reed J, Weisgrau K, Rakasz E, Loffredo J, Piaskowski S, et al. Effective simian immunodeficiency virus-specific CD8+ T cells lack an easily detectable, shared characteristic. J Virol. 2010;84:753-64 pubmed publisher
Jones R, Yue F, Gu X, Hunter D, Mujib S, Gyenes G, et al. Human immunodeficiency virus type 1 escapes from interleukin-2-producing CD4+ T-cell responses without high-frequency fixation of mutations. J Virol. 2009;83:8722-32 pubmed publisher
Chang W, Kim J, Kim Y, Kim Y, Lee J, Azuma M, et al. Cutting edge: Programmed death-1/programmed death ligand 1 interaction regulates the induction and maintenance of invariant NKT cell anergy. J Immunol. 2008;181:6707-10 pubmed
Zahn R, Rett M, Korioth Schmitz B, Sun Y, Buzby A, Goldstein S, et al. Simian immunodeficiency virus (SIV)-specific CD8+ T-cell responses in vervet African green monkeys chronically infected with SIVagm. J Virol. 2008;82:11577-88 pubmed publisher
image
image 1 :
LifeSpan Biosciences LS-C40800 image 1
PHA-stimulated (day-3) human peripheral blood lymphocytes stained with purified EH12.2H7, followed by anti-mouse IgG FITC
product information
AntibodyID :
40502
AntibodyName :
LS-C40800
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
PDCD1 / CD279 / PD-1 Antibody (clone EH12.2H7) LS-C40800
ClonalityDesc :
Monoclonal
CloneName :
EH12.2H7
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.2, 0.09% Sodium Azide
PurificationDesc :
Affinity purified
RecommendedStorageDesc :
Store at 4°C. Store undiluted.
IsotypeName :
IgG1
Gene :
PDCD1 / CD279 / PD-1
StandardGeneSymbol :
PDCD1
gene family :
Apoptosis
Reactivity :
Human
Usage :
Flo
ShortWebDescription :
PD-1 antibody LS-C40800 is an unconjugated mouse monoclonal antibody to human PD-1 (PDCD1 / CD279). Validated for Flow. Cited in 7 publications.
Synonyms :
PDCD1, CD279, HPD-1, HPD-l, PD1, Protein PD-1, SLEB2, PD-1, CD279 antigen, Programmed cell death 1
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.