product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
IGF1 Antibody (clone SPM406) LS-C392250
catalog :
LS-C392250
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SPM406
reactivity :
human
application :
immunocytochemistry, flow cytometry
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
Ludwig S, Smits N, van der Veer G, Bremer M, Nielen M. Multiple protein biomarker assessment for recombinant bovine somatotropin (rbST) abuse in cattle. PLoS ONE. 2012;7:e52917 pubmed publisher
product information
AntibodyID :
404443
AntibodyName :
LS-C392250
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IGF1 Antibody (clone SPM406) LS-C392250
Specificity :
Human IGF1
ClonalityDesc :
Monoclonal
CloneName :
SPM406
AntibodyModification :
Unconjugated
PresentationDesc :
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
ImmunogenType :
Purified protein
ImmunogenDesc :
Purified human IGF1 protein.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 2°C to 8°C.
IsotypeName :
IgG1,k
Gene :
IGF1
StandardGeneSymbol :
IGF1
gene family :
Hormone
Reactivity :
Rabbit, Mouse, Rat, Human
Usage :
Flo (0.5 - 1 µg/10E6 cells), IF (1 - 2 µg/ml)
ShortWebDescription :
IGF1 antibody LS-C392250 is an unconjugated mouse monoclonal antibody to IGF1 from human. It is reactive with human, mouse, rat and other species. Validated for Flow and IF. Cited in 1 publication.
UsageText :
This antibody is specific to Insulin-like Growth Factor (IGF1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon. The optimal dilution of the IGF-1 antibody for each application should be determined by the researcher.
Synonyms :
IGF1, IGF-IA, IGF-IB, IGFI, IBP1, IGF-I, Insulin-like growth factor 1, Insulin-like growth factor I, Insulin-like growth factor IA, Insulin-like growth factor IB, Mechano growth factor, Somatomedin-C, IGF1A, MGF
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.