product summary
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company name :
LifeSpan Biosciences
product type :
antibody
product name :
SMMHC / MYH11 Antibody (clone MYH11/923) LS-C390741
catalog :
LS-C390741
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MYH11/923
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Reference
Henry G, Malewska A, Joseph D, Malladi V, Lee J, Torrealba J, et al. A Cellular Anatomy of the Normal Adult Human Prostate and Prostatic Urethra. Cell Rep. 2018;25:3530-3542.e5 pubmed publisher
product information
AntibodyID :
402934
AntibodyName :
LS-C390741
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
SMMHC / MYH11 Antibody (clone MYH11/923) LS-C390741
Specificity :
Human SMMHC / MYH11
ClonalityDesc :
Monoclonal
CloneName :
MYH11/923
AntibodyModification :
Unconjugated
PresentationDesc :
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant human protein.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 2°C to 8°C.
IsotypeName :
IgG1
Gene :
SMMHC / MYH11
StandardGeneSymbol :
MYH11
Reactivity :
Rat, Human
Usage :
Flo (0.5 - 1 µg/10E6 cells), IF (0.5 - 1 µg/ml), IHC, IHC-P (0.5 - 1 µg/ml)
ShortWebDescription :
MYH11 antibody LS-C390741 is an unconjugated mouse monoclonal antibody to MYH11 (SMMHC) from human. It is reactive with human and rat. Validated for Flow, IF and IHC. Cited in 1 publication.
UsageText :
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors. Optimal dilution of the SMMHC antibody should be determined by the researcher. Staining of formalin/paraffin tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.
Synonyms :
MYH11, AAT4, FAA4, KIAA0866, Myosin-11, Myosin heavy chain 11, SMHC, SMMHC
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.