antibody

MUC5AC Antibody (clone 1-13M1) LS-C390690

LS-C390690

monoclonal

mouse

nonconjugated

1-13M1

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

LS-C390690

Human

Mouse

MUC5AC Antibody (clone 1-13M1) LS-C390690

Human MUC5AC

Monoclonal

1-13M1

Unconjugated

1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide

M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient.

Protein G purified

Store at 2°C to 8°C.

IgG1,k

MUC5AC

MUC5AC

Chicken, Bovine, Rabbit, Mouse, Rat, Human, Monkey

Pig, Hedgehog

Flo (0.5 - 1 µg/10E6 cells), IF (1 - 2 µg/ml), IHC, IHC-Fr (0.5 - 1 µg/ml)

MUC5AC antibody LS-C390690 is an unconjugated mouse monoclonal antibody to MUC5AC from human. It is reactive with human, mouse, rat and other species. Validated for Flow, IF and IHC. Cited in 1 publication.

This mAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC). Its epitope is located in the peptide core of MUC5AC. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. mAb 1-13M1 pairs with mAb 9-13M1 to measure MUC5AC protein by ELISA. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas. Optimal dilution of the MUC5AC antibody should be determined by the researcher.

MUC5AC, Gastric mucin, Major airway glycoprotein, Muc5/5ac, Mucin-5AC, LeB, Lewis B blood group antigen, Tracheobronchial mucin, TBM, MUC-5AC, MUC5

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