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company name :
LifeSpan Biosciences
product type :
antibody
product name :
HLA-DR Antibody (clone 169-1B5.2) LS-C390326
catalog :
LS-C390326
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
169-1B5.2
reactivity :
human
application :
immunocytochemistry, flow cytometry
more info or order :
LifeSpan Biosciences product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
Rombach Riegraf V, Karle A, Wolf B, Sordé L, Koepke S, Gottlieb S, et al. Aggregation of human recombinant monoclonal antibodies influences the capacity of dendritic cells to stimulate adaptive T-cell responses in vitro. PLoS ONE. 2014;9:e86322 pubmed publisher
product information
AntibodyID :
402519
AntibodyName :
LS-C390326
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
HLA-DR Antibody (clone 169-1B5.2) LS-C390326
Specificity :
Human HLA-DR.
ClonalityDesc :
Monoclonal
CloneName :
169-1B5.2
AntibodyModification :
Unconjugated
PresentationDesc :
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
ImmunogenType :
Cells
ImmunogenDesc :
Human peripheral blood leukocytes were used as the immunogen for the HLA-DR antibody.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 2°C to 8°C.
IsotypeName :
IgG2b,k
Gene :
HLA-DR
Reactivity :
Bovine, Human
Usage :
Flo (0.5 - 1 µg/10E6 cells), IF (0.5 - 1 µg/ml)
ShortWebDescription :
HLA-DR antibody LS-C390326 is an unconjugated mouse monoclonal antibody to HLA-DR from human. It is reactive with human and bovine. Validated for Flow and IF. Cited in 1 publication.
UsageText :
This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Optimal dilution of the HLA-DR antibody should be determined by the researcher.
SalesRegion :
Worldwide
more info or order :
LifeSpan Biosciences product webpage
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.