RYR2 / Ryanodine Receptor 2 Antibody (phospho-Ser2808) LS-C358303 | LifeSpan Biosciences LS-C358303 product information

product summary

company name :

LifeSpan Biosciences

product type :

antibody

product name :

RYR2 / Ryanodine Receptor 2 Antibody (phospho-Ser2808) LS-C358303

catalog :

LS-C358303

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

LifeSpan Biosciences product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human	Wu Y, Si F, Ji X, Jiang K, Song S, Yi Q. Cardiac Protection of Valsartan on Juvenile Rats with Heart Failure by Inhibiting Activity of CaMKII via Attenuating Phosphorylation. Biomed Res Int. 2017;2017:4150158 pubmed publisher

image

image 1 :

Western blot analysis of Ryanodine Receptor 2 (pS2808) expression in U251 (A) whole cell lysates.

image 2 :

Immunohistochemical analysis of Ryanodine Receptor 2 (pS2808) staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP-conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.

image 3 :

Immunofluorescent analysis of Ryanodine Receptor 2 (pS2808) staining in U251 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

product information

AntibodyID :

369949

AntibodyName :

LS-C358303

TargetSpecies :

Human

Host Species :

Rabbit

Product Name :

RYR2 / Ryanodine Receptor 2 Antibody (phospho-Ser2808) LS-C358303

Specificity :

Recognizes endogenous levels of Ryanodine Receptor 2 (pS2808) protein.

ClonalityDesc :

Polyclonal

AntibodyModification :

Unconjugated

AntigenModification :

pSer2808

PresentationDesc :

PBS, pH 7.3, 0.01% Sodium Azide, 30% Glycerol

ImmunogenType :

Synthetic peptide - KLH conjugated

ImmunogenDesc :

KLH-conjugated synthetic peptide encompassing a sequence within the central region of human Ryanodine Receptor 2 (pS2808).

PurificationDesc :

Immunoaffinity purified

RecommendedStorageDesc :

Store at -20°C. Aliquot to avoid freeze/thaw cycles.

Gene :

RYR2 / Ryanodine Receptor 2

BlockingPeptide :

LS-E43472

StandardGeneSymbol :

RYR2

gene family :

Ion Channel

Subfamily :

Ryanodine receptor

Reactivity :

Rabbit, Mouse, Rat, Human

Usage :

ICC (1:100 - 1:500), IF, IHC, IHC-P (1:100 - 1:200), WB (1:500 - 1:1000)

ShortWebDescription :

Ryanodine Receptor 2 antibody LS-C358303 is an unconjugated rabbit polyclonal antibody to Ryanodine Receptor 2 (RYR2) (pSer2808) from human. It is reactive with human, mouse, rat and other species. Validated for ICC, IF, IHC and WB. Cited in 1 publication.

Synonyms :

RYR2, ARVD2, ARVC2, Cardiac ryanodine receptor, Cardiac-type ryaodine receptor, HRYR-2, RYR-2, VTSIP, Islet-type ryanodine receptor, Kidney-type ryanodine receptor, Ryanodine receptor, Ryanodine receptor 2, Ryanodine receptor 2 (cardiac), RyR, Type 2 ryanodine receptor

SalesRegion :

Worldwide

more info or order :

LifeSpan Biosciences product webpage

company information

LifeSpan Biosciences

2401 Fourth Avenue, Suite 900
Seattle, WA 98121

CustomerSupport@lsbio.com

https://www.lsbio.com

1-206-464-1554

headquarters: USA

Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.