This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
NKX2-1 / Thyroid-Specific TF Antibody (clone 8G7G3/1) LS-C358075
catalog :
LS-C358075
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
8G7G3/1

The same clone is also sold as:
reactivity :
human, rat
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
product information
AntibodyID :
369620
AntibodyName :
LS-C358075
TargetSpecies :
Rat
Host Species :
Mouse
Product Name :
NKX2-1 / Thyroid-Specific TF Antibody (clone 8G7G3/1) LS-C358075
Specificity :
Rat TTF-1 / Thyroid-Specific TF
ClonalityDesc :
Monoclonal
CloneName :
8G7G3/1
AntibodyModification :
Unconjugated
PresentationDesc :
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Rat full length TTF1 / NKX2.1 recombinant protein.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 2°C to 8°C.
IsotypeName :
IgG1,k
Gene :
NKX2-1 / Thyroid-Specific TF
StandardGeneSymbol :
NKX2-1
Reactivity :
Mouse, Rat, Human
Usage :
Flo (0.5 - 1 µg/10E6 cells), IF (0.5 - 1 µg/ml), IHC, IHC-P (0.5 - 1 µg/ml)
ShortWebDescription :
Thyroid-Specific TF antibody LS-C358075 is an unconjugated mouse monoclonal antibody to Thyroid-Specific TF (NKX2-1) from rat. It is reactive with human, mouse and rat. Validated for Flow, IF and IHC.
UsageText :
This mAb recognizes a protein of 40kDa, identified as Thyroid transcription factor 1. TTF1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. antibody to TTF1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. The antibody can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF1 reactivity is also seen in thyroid malignancies. ELISA: Order BSA-free format for coating.
Synonyms :
NKX2-1, BCH, Benign chorea, Homeobox protein Nkx-2.1, NK-2, NKX2.1, NK-2 homolog A, Thyroid transcription factor 1, NK2 homeobox 1, TTF-1, BHC, Thyroid nuclear factor 1, TITF1, NKX2A, TEBP
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.