This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
TIMP3 Antibody (aa198-211) LS-C358066
catalog :
LS-C358066
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA
product information
AntibodyID :
369611
AntibodyName :
LS-C358066
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
TIMP3 Antibody (aa198-211) LS-C358066
Specificity :
Human TIMP3
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa198-211
PresentationDesc :
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A synthetic peptide corresponding to a sequence at the C-Terminus of human TIMP3(198-211 aa WAPPDKSIINATDP). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Ferret, Sheep, Cat, Bovine, Pig, Dog (100%); Mouse, Bat, Hamster, Opossum, Zebra finch, Chicken, Lizard (93%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.
ResuspensionLiquidDesc :
Reconstitute in sterile distilled water.
IsotypeName :
IgG
Gene :
TIMP3
StandardGeneSymbol :
TIMP3
Reactivity :
Dog, Sheep, Bovine, Rat, Pig, Gibbon, Chimpanzee, Human, Monkey
Usage :
ELISA (0.1 - 0.5 µg/ml), WB (0.5 - 1 µg/ml)
ShortWebDescription :
TIMP3 antibody LS-C358066 is an unconjugated rabbit polyclonal antibody to TIMP3 (aa198-211) from human. It is reactive with human, rat, bovine and other species. Validated for ELISA and WB.
UsageText :
The tissue inhibitors of metalloproteinases(TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy(SFD).
Synonyms :
TIMP3, HSMRK222, K222TA2, MIG-5 protein, K222, SFD, Metalloproteinase inhibitor 3, Protein MIG-5, TIMP-3
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.