This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
TG / Thyroglobulin Antibody (clone 2H11 or TGB04) LS-C358060
catalog :
LS-C358060
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2H11 or TGB04
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
product information
AntibodyID :
369605
AntibodyName :
LS-C358060
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
TG / Thyroglobulin Antibody (clone 2H11 or TGB04) LS-C358060
Specificity :
Human TG / Thyroglobulin
ClonalityDesc :
Monoclonal
CloneName :
2H11 or TGB04
AntibodyModification :
Unconjugated
PresentationDesc :
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
ImmunogenType :
Cells
ImmunogenDesc :
Human thyroid follicular cells were used as the immunogen for this Thyroglobulin antibody.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 2°C to 8°C.
IsotypeName :
IgG1,k
Gene :
TG / Thyroglobulin
StandardGeneSymbol :
TG
Reactivity :
Mouse, Rat, Human
Usage :
ELISA, Flo (0.5 - 1 µg/10E6 cells), IHC, IHC-P (0.5 - 1 µg/ml), WB (0.5 - 1 µg/ml)
ShortWebDescription :
Thyroglobulin antibody LS-C358060 is an unconjugated mouse monoclonal antibody to Thyroglobulin (TG) from human. It is reactive with human, mouse and rat. Validated for ELISA, Flow, IHC and WB.
UsageText :
Thyroglobulin is a 660kDa dimeric pre-protein with mutiple glycosylation sites, detected at ~300kDa in western blot. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for thyroglobulin antibody even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently thyroglobulin antibody negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Thyroglobulin antibody, combined with calcitonin antibody, can identify medullary carcinomas of the thyroid. Furthermore, thyroglobulin antibody, combined with TTF1 antibody, can be a reliable marker to differentiate between primary thyroid and lung neoplasms. ELISA: Order BSA-free format for coating.
Synonyms :
TG, AITD3, TDH3, Thyroglobulin, TGN
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.
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