This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
MAPKAP1 / MIP1 Antibody (C-Terminus) LS-C358044
catalog :
LS-C358044
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
product information
AntibodyID :
369589
AntibodyName :
LS-C358044
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
MAPKAP1 / MIP1 Antibody (C-Terminus) LS-C358044
Specificity :
Human SIN1 / MIP1
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
C-Terminus
PresentationDesc :
1X PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
A recombinant protein fragment from the C-Terminus of human SIN1.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG
Gene :
MAPKAP1 / MIP1
StandardGeneSymbol :
MAPKAP1
gene family :
Protein Kinase
Reactivity :
Mouse, Dog, Rat, Human
Usage :
WB (1 - 3 µg/ml)
ShortWebDescription :
MIP1 antibody LS-C358044 is an unconjugated rabbit polyclonal antibody to MIP1 (MAPKAP1) (C-Terminus) from human. It is reactive with human, mouse, rat and other species. Validated for WB.
UsageText :
mTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.
Synonyms :
MAPKAP1, MSIN1, SAPK-interacting protein 1, SIN1b, TORC2 subunit MAPKAP1, Ras inhibitor MGC2745, SIN1, SIN1g, JC310, MEKK2-interacting protein 1, Mip1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.