This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
S100A8 / MRP8 Antibody (N-Terminus, clone SA6279) LS-C358038
catalog :
LS-C358038
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SA6279
reactivity :
human
application :
western blot
product information
AntibodyID :
369583
AntibodyName :
LS-C358038
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
S100A8 / MRP8 Antibody (N-Terminus, clone SA6279) LS-C358038
Specificity :
Human S100A8 / MRP8
ClonalityDesc :
Monoclonal
CloneName :
SA6279
AntibodyModification :
Unconjugated
AntigenModification :
N-Terminus
PresentationDesc :
1X PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
A recombinant protein fragment from the N-Terminus of human S100A8.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1,k
Gene :
S100A8 / MRP8
StandardGeneSymbol :
S100A8
Reactivity :
Human
Usage :
WB (2 - 4 µg/ml)
ShortWebDescription :
MRP8 antibody LS-C358038 is an unconjugated mouse monoclonal antibody to human MRP8 (S100A8) (N-Terminus). Validated for WB.
UsageText :
The S100 family of proteins are found in vertebrates and are characterized by two calcium-binding sites that have a helix-loop-helix conformation. The family of 24 is divided into three subgroups based on function: those with intracellular, intracellular plus extracellular, and extracellular regulatory effects. The calcium-binding protein S100A8, also called MRP8 or Myeloid-related protein 8, and Calgranulin A, forms a heterodimer with S100A9, called Calprotectin. The heterodimer is expressed by granulocytes, monocytes, and early differentiation states of macrophages, and is known to be an important pro-inflammatory mediator in acute and chronic inflammation. S100A8 and 9 are DAMPs, or Damage-associated molecular pattern molecules, and are able to activate receptors of the innate immune system, one being TLR4.
Synonyms :
S100A8, 60B8AG, CFAG, CAGA, Calgranulin A, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen, CGLA, L1Ag, NIF, p8, Protein S100-A8, MRP8, Urinary stone protein band A, CP-10, MA387, MRP-8
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.