This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
TNFRSF11A / RANK Antibody (aa29-44) LS-C358032
catalog :
LS-C358032
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
AntibodyID :
369577
AntibodyName :
LS-C358032
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
TNFRSF11A / RANK Antibody (aa29-44) LS-C358032
Specificity :
Human TNFRSF11A / RANK
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa29-44
PresentationDesc :
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A synthetic peptide corresponding to a sequence at the N-Terminus of human RANK (29-44 aa QIAPPCTSEKHYEHLG). Percent identity by BLAST analysis: Human, Gorilla (100%); Baboon, Monkey (94%); Gibbon (88%); Orangutan, Marmoset (81%); Rat (69%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.
ResuspensionLiquidDesc :
Reconstitute in sterile distilled water.
IsotypeName :
IgG
Gene :
TNFRSF11A / RANK
StandardGeneSymbol :
TNFRSF11A
gene family :
TNF Receptor
Reactivity :
Human
Usage :
IHC, IHC-P (0.5 - 1 µg/ml), WB (0.5 - 1 µg/ml)
ShortWebDescription :
RANK antibody LS-C358032 is an unconjugated rabbit polyclonal antibody to human RANK (TNFRSF11A) (aa29-44). Validated for IHC and WB.
UsageText :
Receptor Activator of Nuclear Factor K B, also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is also expressed on dendritic cells and facilitates immune signaling. RANKL (Receptor Activator for Nuclear Factor K B Ligand) is found on the surface of stromal cells, osteoblasts, and T cells. By analysis of somatic cell and radiation hybrid panels, Anderson et al.(1997) mapped the RANK gene to 18q22.1.
Synonyms :
TNFRSF11A, CD265, CD265 antigen, ODFR, LOH18CR1, OPTB7, OSTS, PDB2, RANK, Receptor activator of NF-KB, TRANCER, FEO, OFE
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.