This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
PGF / PLGF Antibody (clone PLGF94) LS-C358022
catalog :
LS-C358022
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PLGF94

The same clone is also sold as:
reactivity :
human
product information
AntibodyID :
369567
AntibodyName :
LS-C358022
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
PGF / PLGF Antibody (clone PLGF94) LS-C358022
Specificity :
Human PGF / PLGF
ClonalityDesc :
Monoclonal
CloneName :
PLGF94
AntibodyModification :
Unconjugated
PresentationDesc :
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant human PLGF protein.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 2°C to 8°C.
IsotypeName :
IgG1,k
Gene :
PGF / PLGF
StandardGeneSymbol :
PGF
gene family :
PDGF
Reactivity :
Human
Usage :
ELISA, Func
ShortWebDescription :
PLGF antibody LS-C358022 is an unconjugated mouse monoclonal antibody to human PLGF (PGF). Validated for ELISA and Func.
UsageText :
The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include fibroblast-, platelet derived-, vascular endothelial- and placenta- growth factor (PLGF). Like vascular endothelial growth factor, several PLGF variants have been shown to arise from alternative mRNA splicings. Evidence has suggested VEGF to be an obligatory component in PLGF signaling. While VEGF homodimers and VEGF/PLGF heterodimers function as potent mediators of mitogenic and chemotactic responses in endothelial cells, PLGF homodimers are effectual only at extremely high concentrations. Indeed, many of the physiological effects attributed to VEGF may actually be a result of VEGF/PLGF. VEGF and PLGF share a common receptor, Flt-1, and may also activate Flk-1/KDR. ELISA: Order BSA-free antibody format for coating.
Synonyms :
PGF, D12S1900, PGFL, PlGF-2, Placental growth factor, Placental growth factor-like, PLGF, Placenta growth factor, SHGC-10760
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.