This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
PAX6 Antibody (clone PAX6/496) LS-C358010
catalog :
LS-C358010
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PAX6/496

The same clone is also sold as:
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
product information
AntibodyID :
369555
AntibodyName :
LS-C358010
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
PAX6 Antibody (clone PAX6/496) LS-C358010
Specificity :
Human PAX6
ClonalityDesc :
Monoclonal
CloneName :
PAX6/496
AntibodyModification :
Unconjugated
PresentationDesc :
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant human PAX6 protein.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 2°C to 8°C.
IsotypeName :
IgG1,k
Gene :
PAX6
StandardGeneSymbol :
PAX6
Reactivity :
Chicken, Mouse, Rat, Human
Usage :
Flo (0.5 - 1 µg/10E6 cells), IF (0.5 - 1 µg/ml), IHC, IHC-Fr (0.5 - 1 µg/ml), WB (0.5 - 1 µg/ml)
ShortWebDescription :
PAX6 antibody LS-C358010 is an unconjugated mouse monoclonal antibody to PAX6 from human. It is reactive with human, mouse, rat and other species. Validated for Flow, IF, IHC and WB.
UsageText :
PAX genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the PAX6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. PAX6 is involved in other anterior segment malformations besides aniridia, such as Peters' anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The PAX6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human PAX6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain. ELISA: Order BSA-free antibody format for coating.
Synonyms :
PAX6, AN2, D11S812E, MGDA, Oculorhombin, Paired box 6, Paired box homeotic gene-6, AN, Aniridia type II protein, WAGR, Paired box protein Pax-6
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.