This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
PECAM-1 / CD31 Antibody (clone C31.7) LS-C358009
catalog :
LS-C358009
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C31.7

The same clone is also sold as:
reactivity :
human
application :
western blot, flow cytometry, immunohistochemistry - paraffin section
product information
AntibodyID :
369554
AntibodyName :
LS-C358009
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
PECAM-1 / CD31 Antibody (clone C31.7) LS-C358009
Specificity :
Human PECAM-1 / CD31
ClonalityDesc :
Monoclonal
CloneName :
C31.7
AntibodyModification :
Unconjugated
PresentationDesc :
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Human recombinant PECAM-1 / CD31 protein.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 2°C to 8°C.
IsotypeName :
IgG1,k
Gene :
PECAM-1 / CD31
StandardGeneSymbol :
PECAM1
Reactivity :
Human
Usage :
Flo (1 - 2 µg/10E6 cells), IHC-P (1 - 2 µg/ml), WB (1 - 2 µg/ml)
ShortWebDescription :
CD31 antibody LS-C358009 is an unconjugated mouse monoclonal antibody to human CD31 (PECAM-1). Validated for Flow, IHC and WB.
UsageText :
PECAM-1, or platelet endothelial cell adhesion molecule-1, also called CD31, is made up of six extracellular immunoglobulin-like domains, a single transmembrane domain, and a cytoplasmic domain containing serine and tyrosine residues that when phosphorylated, activate the molecules signaling function. It is expressed on platelets, monocytes, neutrophils, bone marrow macrophage and dendritic cells precursors, and at the intracellular junction of endothelial cells. PECAM-1, on the endothelial lining of blood vessels, helps maintain the vascular barrier. In response to inflammatory mediators, the endothelial pull away from each other allowing fluid, inflammatory cells and proteins into the extravascular space. The inflammatory response fades as adhesion of neighboring cells increase. PECAM-1 also plays an important role in angiogenesis, promoting endothelial cell motility, junctional development and capillary morphogenesis. ELISA: Order BSA-free format for coating.
Synonyms :
PECAM1, CD31, CD31 antigen, EndoCAM, PECA1, PECAM-1, GPIIA
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.