This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
PER2 Antibody LS-C358007
catalog :
LS-C358007
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
product information
AntibodyID :
369552
AntibodyName :
LS-C358007
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
PER2 Antibody LS-C358007
Specificity :
Human PER2
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide.
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Human recombinant protein (aa N13-K330).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.
ResuspensionLiquidDesc :
Reconstitute in sterile distilled water.
IsotypeName :
IgG
Gene :
PER2
StandardGeneSymbol :
PER2
Reactivity :
Human
Usage :
WB (0.5 - 1 µg/ml)
ShortWebDescription :
PER2 antibody LS-C358007 is an unconjugated rabbit polyclonal antibody to human PER2. Validated for WB.
UsageText :
The PER2 gene encodes the period circadian protein homolog 2 protein in humans. This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. It has been showed that PER2 can positively stimulate activity of the Bmal1-Npas2 transcription complex and, in turn, Npas2 transcriptionally regulates delta-aminolevulinate synthase. It is involved in a negative-feedback loop that attenuates estrogen stimulation and links the circadian cycle to estrogen receptor signaling. The rhythmic levels of PER2 are critical for circadian oscillations in cells and intact organisms. The protein also functions in tumor suppression by regulating DNA damage-responsive pathways.
Synonyms :
PER2, HPER2, Period homolog 2 (Drosophila), Period 2, KIAA0347, Period (Drosophila) homolog 2, Period circadian clock 2, Period circadian protein 2, FASPS
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.