This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
MYD88 Antibody LS-C357983
catalog :
LS-C357983
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
AntibodyID :
369528
AntibodyName :
LS-C357983
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
MYD88 Antibody LS-C357983
Specificity :
Human MYD88
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide.
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Human recombinant protein (aa A44-F264).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.
ResuspensionLiquidDesc :
Reconstitute in sterile distilled water.
IsotypeName :
IgG
Gene :
MYD88
StandardGeneSymbol :
MYD88
Reactivity :
Mouse, Rat, Human
Usage :
IHC, IHC-P (0.5 - 1 µg/ml), WB (0.5 - 1 µg/ml)
ShortWebDescription :
MYD88 antibody LS-C357983 is an unconjugated rabbit polyclonal antibody to MYD88 from human. It is reactive with human, mouse and rat. Validated for IHC and WB.
UsageText :
MYD88(MYELOID DIFFERENTIATION PRIMARY RESPONSE GENE 88), is a protein that, in humans, is encoded by the MYD88 gene. MyD88 is a key downstream adapter for most Toll-like receptors (TLRs) and interleukin-1 receptors (IL1Rs). And it is mapped on 3p22.2. MYD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. Overexpression of MYD88 caused an increase in the level of transcription from the interleukin-8 promoter. The C-terminal domain of MYD88 has significant sequence similarity to the cytoplasmic domain of IL1RAP. Inhibiting the IL1R-MYD88 pathway in vivo could block the damage from acute inflammation that occurs in response to sterile cell death, and do so in a way that might not compromise tissue repair or host defense against pathogens.
Synonyms :
MYD88, MYD88D
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.