This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
Mitochondria Antibody (clone 113-1) LS-C357971
catalog :
LS-C357971
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
113-1
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
product information
AntibodyID :
369516
AntibodyName :
LS-C357971
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
Mitochondria Antibody (clone 113-1) LS-C357971
Specificity :
Human Mitochondrial Marker
ClonalityDesc :
Monoclonal
CloneName :
113-1
AntibodyModification :
Unconjugated
PresentationDesc :
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
ImmunogenType :
Purified protein
ImmunogenDesc :
A semi-purified mitochondrial preparation.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 2°C to 8°C.
IsotypeName :
IgG1,k
Gene :
Mitochondria
Reactivity :
Human
NonReactiveSpecies :
Mouse, Rat
Usage :
IF (0.5 - 1 µg/ml), IHC, IHC-P (0.5 - 1 µg/ml), IP, WB (0.25 - 0.5 µg/ml)
ShortWebDescription :
Mitochondria antibody LS-C357971 is an unconjugated mouse monoclonal antibody to human Mitochondria. Validated for IF, IHC, IP and WB.
UsageText :
Clone 113-1 antibody recognizes a 60kDa antigen that is a mitochondrial marker in human cells. Immunostaining produces a spaghetti-like pattern in normal and malignant cells. This mitochondrial marker antibody is an excellent marker for human cells in xenographic model research. Abundant granular eosinophilic cytoplasm is a common feature of renal oncocytoma, chromophobe renal cell carcinoma, eosinophilic variant of papillary renal cell carcinoma, and the granular variant of clear cell renal cell carcinoma (RCC). The chief reason for their distinction from one another is the difference in their biologic behavior. However, precise characterization may be difficult in some cases because of overlapping morphologic features. Immunostaining pattern with this mitochondrial marker antibody has been reported as a useful discriminatory adjunct in the complex differential diagnosis of granular renal cell tumors. Salivary gland tumors usually show great variability both in their morphopathology as well as their clinical behavior. One study highlights the usefulness of this mitochondrial marker antibody to facilitate the classification of salivary tumors, an aspect that may sometimes have not only diagnostic implications, but also prognostic.
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.