This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
ITGB4 / Integrin Beta 4 Antibody (clone UM-A9) LS-C357939
catalog :
LS-C357939
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
UM-A9

The same clone is also sold as:
reactivity :
human
application :
immunocytochemistry, neutralization, flow cytometry
product information
AntibodyID :
369484
AntibodyName :
LS-C357939
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
ITGB4 / Integrin Beta 4 Antibody (clone UM-A9) LS-C357939
Specificity :
Human ITGB4 / Integrin Beta 4
ClonalityDesc :
Monoclonal
CloneName :
UM-A9
AntibodyModification :
Unconjugated
PresentationDesc :
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
ImmunogenType :
Cells
ImmunogenDesc :
The human squamous cell carcinoma line (UM-SCC1).
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 2°C to 8°C.
IsotypeName :
IgG2a,k
Gene :
ITGB4 / Integrin Beta 4
StandardGeneSymbol :
ITGB4
gene family :
Integrin
Reactivity :
Human
Usage :
Block, Flo (0.5 - 1 µg/10E6 cells), IF (0.5 - 1 µg/ml)
ShortWebDescription :
Integrin Beta 4 antibody LS-C357939 is an unconjugated mouse monoclonal antibody to human Integrin Beta 4 (ITGB4). Validated for Block, Flow and IF.
UsageText :
This antibody recognizes a protein of 205kDa, which is identified as integrin beta 4 (ITGB4) and CD104. Its epitope is localized in the extracellular domain of integrin beta 4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. ELISA: Order BSA-free format for coating.
Synonyms :
ITGB4, CD104, Integrin beta-4, Integrin Beta 4, gp150, CD104 antigen, Integrin beta-4 subunit, Integrin, beta 4
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.