This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
IKBKB / IKK2 / IKK Beta Antibody (clone IKB355) LS-C357936
catalog :
LS-C357936
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
IKB355
reactivity :
human
application :
western blot
product information
AntibodyID :
369481
AntibodyName :
LS-C357936
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
IKBKB / IKK2 / IKK Beta Antibody (clone IKB355) LS-C357936
Specificity :
Human IKBKB / IKK2 / IKK Beta
ClonalityDesc :
Monoclonal
CloneName :
IKB355
AntibodyModification :
Unconjugated
PresentationDesc :
1X PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
A recombinant protein fragment of IKKb.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG1,k
Gene :
IKBKB / IKK2 / IKK Beta
StandardGeneSymbol :
IKBKB
gene family :
Protein Kinase
Subfamily :
IKAPPAB
Reactivity :
Mouse, Human
Usage :
WB (2 - 4 µg/ml)
ShortWebDescription :
IKK Beta antibody LS-C357936 is an unconjugated mouse monoclonal antibody to IKK Beta (IKBKB / IKK2) from human. It is reactive with human and mouse. Validated for WB.
UsageText :
NF-kB is sequestered in the cytoplasm by IkBa, unable to translocate to the nucleus. IkB is part of the canonical pathway for NF-kB activation. IKKb is part of the IkB kinase complex, along with a second catalytic subunit, IKKa, and a regulatory subunit, IKKg. Along with IKKa, IKKb phosphorylates IkBa leading to its degradation and release of inhibition of NF-kB. The RELA subunit of active NF-kB is then free to enter the nucleus and initiate a number of signaling cascades.
Synonyms :
IKBKB, Ikk 2, IKK-B, IKK2, IKKbeta, NFKBIKB, I-kappa-B kinase 2, IKKB, I-kappa-B-kinase beta, Ikb kinase-beta, IKK Beta, IKK-beta
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.