This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
GFAP Antibody (aa417-432) LS-C357892
catalog :
LS-C357892
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
AntibodyID :
369437
AntibodyName :
LS-C357892
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
GFAP Antibody (aa417-432) LS-C357892
Specificity :
Human GFAP
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
aa417-432
PresentationDesc :
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A synthetic peptide corresponding to a sequence at the C-Terminus of human GFAP (417-432 aa DGEVIKESKQEHKDVM). Percent identity by BLAST analysis: Human, Gibbon, Galago, Marmoset, Rat, Cat, Rabbit, Horse (100%); Pig, Dog (94%); Mouse (88%); Opossum (81%).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
ResuspensionLiquidDesc :
It is recommended that deionized water (200ul) be added to the vial to prepare a stock solution of 0.5mg/mL.
IsotypeName :
IgG
Gene :
GFAP
StandardGeneSymbol :
GFAP
Reactivity :
Rabbit, Mouse, Rat, Horse, Gibbon, Human, Monkey
Usage :
IHC, IHC-P (0.5 - 1 µg/ml), WB (0.5 - 1 µg/ml)
ShortWebDescription :
GFAP antibody LS-C357892 is an unconjugated rabbit polyclonal antibody to GFAP (aa417-432) from human. It is reactive with human, mouse, rat and other species. Validated for IHC and WB.
UsageText :
Glial fibrillary acidic protein is an intermediate-filament (IF) protein that is highly specific for cells of astroglial lineage, although its tissue-specific role is speculative. Expression is also seen in rat kidney glomeruli and peritubular fibroblasts, leydig cells of testis, skin keratinocytes, osteocytes of bones, chondrocytes of epiglottis, bronchus, and stellate-shaped cells of the pancreas and liver. Its expression is essential for normal white matter architecture and blood-brain barrier integrity, and its absence leads to late-onset CNS dysmyelination. The protein has also been shown to play a role in mitosis by adjusting the filament network present in the cell. During mitosis, there is an increase in the amount of phosphorylated GFAP, and a movement of this modified protein to the cleavage furrow.
Synonyms :
GFAP
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.