This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
DRAM1 / DRAM Antibody (N-Terminus) LS-C357851
catalog :
LS-C357851
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
product information
AntibodyID :
369396
AntibodyName :
LS-C357851
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
DRAM1 / DRAM Antibody (N-Terminus) LS-C357851
Specificity :
Human DRAM1 / DRAM
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
AntigenModification :
N-Terminus
PresentationDesc :
1X PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
A recombinant protein fragment from the N-Terminus of human DRAM.
PurificationDesc :
Protein A purified
RecommendedStorageDesc :
Store at -20°C. Avoid freeze-thaw cycles.
IsotypeName :
IgG
Gene :
DRAM1 / DRAM
StandardGeneSymbol :
DRAM1
gene family :
Cancer
Reactivity :
Mouse, Rat, Human
Usage :
WB (4 - 8 µg/ml)
ShortWebDescription :
DRAM antibody LS-C357851 is an unconjugated rabbit polyclonal antibody to DRAM (DRAM1) (N-Terminus) from human. It is reactive with human, mouse and rat. Validated for WB.
UsageText :
Autophagy is the mechanism by which lysosomes degrade unneeded or dysfunctional cellular components. p53 is a tumor suppressor protein that modulates autophagy and apoptosis. DRAM, or damage regulated autophagy modulator, is a lysosomal protein and effector of p53-mediated cell death. Many tumors show decreased DRAM expression and siRNA knockdown resulted in reduced cell death (Crighton et al, 2006).
Synonyms :
DRAM1, DRAM
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.