This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
KRT6 / CK6 / Cytokeratin 6 Antibody (C-Terminus, clone LHK6) LS-C357841
catalog :
LS-C357841
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
LHK6
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
product information
AntibodyID :
369386
AntibodyName :
LS-C357841
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
KRT6 / CK6 / Cytokeratin 6 Antibody (C-Terminus, clone LHK6) LS-C357841
Specificity :
Human KRT6 / CK6 / Cytokeratin 6
ClonalityDesc :
Monoclonal
CloneName :
LHK6
AntibodyModification :
Unconjugated
AntigenModification :
C-Terminus
PresentationDesc :
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
ImmunogenType :
Synthetic peptide
ImmunogenDesc :
A synthetic peptide of 11 amino acids (GSSTIKYTTTS) from the C-Terminus of human Cytokeratin 6. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Baboon, Monkey, Horse (100%); Marmoset, Mouse, Rat, Ferret, Bat, Hamster, Elephant, Dog (91%); Sheep, Bovine (82%).
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 2°C to 8°C.
IsotypeName :
IgG2a,k
Gene :
KRT6 / CK6 / Cytokeratin 6
Reactivity :
Horse, Orangutan, Gibbon, Human, Chimpanzee
Usage :
Flo (0.5 - 1 µg/10E6 cells), IF (0.5 - 1 µg/ml), IHC, IHC-P (0.5 - 1 µg/ml)
ShortWebDescription :
Cytokeratin 6 antibody LS-C357841 is an unconjugated mouse monoclonal antibody to Cytokeratin 6 (KRT6 / CK6) (C-Terminus) from human. It is reactive with human, chimpanzee, gibbon and other species. Validated for Flow, IF and IHC.
UsageText :
This antibody recognizes a protein of 56kDa, identified as cytokeratin 6 (CK6) or Keratin 6. In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and Cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human Cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies. Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express Cytokeratin 6 and 16. Keratin 6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of Cytokeratin 6 is particularly associated with differentiation. ELISA: Order BSA-free antibody format for coating.
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.