KRT10 / CK10 / Cytokeratin 10 Antibody (clone LH2) LS-C357836 | LifeSpan Biosciences LS-C357836 product information

product summary

company name :

LifeSpan Biosciences

product type :

antibody

product name :

KRT10 / CK10 / Cytokeratin 10 Antibody (clone LH2) LS-C357836

catalog :

LS-C357836

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

LH2

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

LifeSpan Biosciences product webpage

citations: 1

Reference
Ascherman D, Zang Y, Fernandez I, Clark E, Khan W, Martinez L, et al. An Autoimmune Basis for Raynaud's Phenomenon: Murine Model and Human Disease. Arthritis Rheumatol. 2018;70:1489-1499 pubmed publisher

product information

AntibodyID :

369381

AntibodyName :

LS-C357836

TargetSpecies :

Human

Host Species :

Mouse

Product Name :

KRT10 / CK10 / Cytokeratin 10 Antibody (clone LH2) LS-C357836

Specificity :

Human KRT10 / CK10 / Cytokeratin 10

ClonalityDesc :

Monoclonal

CloneName :

LH2

AntibodyModification :

Unconjugated

PresentationDesc :

1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide

ImmunogenDesc :

Skin extract from a human psoriasis patient.

PurificationDesc :

Protein G purified

RecommendedStorageDesc :

Store at 2°C to 8°C.

IsotypeName :

IgG1

Gene :

KRT10 / CK10 / Cytokeratin 10

StandardGeneSymbol :

KRT10

Reactivity :

Mouse, Human

Usage :

Flo (0.5 - 1 µg/10E6 cells), IF (0.5 - 1 µg/ml), IHC, IHC-P (0.5 - 1 µg/ml)

ShortWebDescription :

Cytokeratin 10 antibody LS-C357836 is an unconjugated mouse monoclonal antibody to Cytokeratin 10 (KRT10 / CK10) from human. It is reactive with human and mouse. Validated for Flow, IF and IHC. Cited in 1 publication.

UsageText :

This antibody recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10). cytokeratin 10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of cytokeratin 10 strictly parallels the extent of differentiation. it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, cytokeratin 10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), cytokeratin 10 is detected very frequently. Expression of cytokeratin 10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts. ELISA: Order BSA-free antibody format for coating.

Synonyms :

KRT10, BIE, BCIE, CK10, Cytokeratin 10, Cytokeratin-10, EHK, Keratin-10, KPP, Keratin 10, CK-10, K10

SalesRegion :

Worldwide

more info or order :

LifeSpan Biosciences product webpage

company information

LifeSpan Biosciences

2401 Fourth Avenue, Suite 900
Seattle, WA 98121

CustomerSupport@lsbio.com

https://www.lsbio.com

1-206-464-1554

headquarters: USA

Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.