This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CCND1 / Cyclin D1 Antibody (clone DCS-6, PE) LS-C357829
catalog :
LS-C357829
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
DCS-6

The same clone is also sold as:
reactivity :
human
application :
immunocytochemistry, flow cytometry
product information
AntibodyID :
369374
AntibodyName :
LS-C357829
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
CCND1 / Cyclin D1 Antibody (clone DCS-6, PE) LS-C357829
Specificity :
Human CCND1 / Cyclin D1
ClonalityDesc :
Monoclonal
CloneName :
DCS-6
AntibodyModification :
PE
PresentationDesc :
0.1 mg/ml BSA, 0.05% sodium azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Human recombinant full length cyclin D1 protein
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 2°C to 8°C. Do not freeze.
IsotypeName :
IgG2a,k
Gene :
CCND1 / Cyclin D1
StandardGeneSymbol :
CCND1
Reactivity :
Mouse, Rat, Human, Monkey
Usage :
Flo, IF (1:50 - 1:100)
ShortWebDescription :
Cyclin D1 antibody LS-C357829 is a PE-conjugated mouse monoclonal antibody to Cyclin D1 (CCND1) from human. It is reactive with human, mouse, rat and other species. Validated for Flow and IF.
UsageText :
This antibody recognizes a protein of 36kDa, identified as Cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11. 14)(q13. q32) translocation resulting in over-expression. The antibody is useful in identifying mantle cell lymphomas (Cyclin D1 positive) from CLL/SLL and follicular lymphomas (Cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Synonyms :
CCND1, B-cell lymphoma 1 protein, BCL-1 oncogene, B-cell CLL/lymphoma 1, BCL-1, Cyclin D1, G1/S-specific cyclin-D1, U21B31, PRAD1, BCL1, D11S287E, PRAD1 oncogene
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.