This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CCNB1 / Cyclin B1 Antibody (clone V92.1) LS-C357828
catalog :
LS-C357828
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
V92.1

The same clone is also sold as:
reactivity :
human
application :
immunocytochemistry, immunoprecipitation, flow cytometry
product information
AntibodyID :
369373
AntibodyName :
LS-C357828
TargetSpecies :
Hamster
Host Species :
Mouse
Product Name :
CCNB1 / Cyclin B1 Antibody (clone V92.1) LS-C357828
Specificity :
Hamster CCNB1 / Cyclin B1
ClonalityDesc :
Monoclonal
CloneName :
V92.1
AntibodyModification :
Unconjugated
PresentationDesc :
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
ImmunogenType :
Purified protein
ImmunogenDesc :
Hamster protein.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 2°C to 8°C.
IsotypeName :
IgG1,k
Gene :
CCNB1 / Cyclin B1
StandardGeneSymbol :
CCNB1
Reactivity :
Mouse, Hamster, Human
Usage :
Flo (0.5 - 1 µg/10E6 cells), IF (1 - 2 µg/ml), IP (2 - 4 µg/mg lysate)
ShortWebDescription :
Cyclin B1 antibody LS-C357828 is an unconjugated mouse monoclonal antibody to Cyclin B1 (CCNB1) from hamster. It is reactive with human, mouse and hamster. Validated for Flow, IF and IP.
UsageText :
This antibody recognizes a protein of 55-62kDa, identified as Cyclin B1. In mammals, Cyclin B1 associates with inactive p34cdc2, which facilitates phosphorylation of p34cdc2 at amino acids Thr-14 and Tyr-15. This maintains the inactive state until the end of G2-phase. The inactive Cyclin B1-p34cdc2 complex continues to accumulate in the cytoplasm until the completion of DNA synthesis, when Cdc25, a specific protein phosphatase, dephosphorylates amino acids Thr-14 and Tyr-15 of p34cdc2 rendering the complex active at the G2/M boundary. This mitotic kinase complex remains active until the metaphase/anaphase transition when Cyclin B1 is degraded. This degradation process is ubiquitin-dependent and is necessary for the cell to exit mitosis. Cyclin B1-p34cdc2 plays a critical role in G2 to M transition. ELISA: Order BSA-free antibody format for coating.
Synonyms :
CCNB1, CCNB, Cyclin B1, G2/mitotic-specific cyclin-B1, G2/mitotic-specific cyclin B1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.