This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
SPN / CD43 Antibody LS-C357769
catalog :
LS-C357769
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
AntibodyID :
369314
AntibodyName :
LS-C357769
TargetSpecies :
Human
Host Species :
Rabbit
Product Name :
SPN / CD43 Antibody LS-C357769
Specificity :
Human SPN / CD43
ClonalityDesc :
Polyclonal
AntibodyModification :
Unconjugated
PresentationDesc :
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide.
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Human recombinant protein (aa A272-P400).
PurificationDesc :
Immunoaffinity purified
RecommendedStorageDesc :
Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.
ResuspensionLiquidDesc :
Reconstitute in sterile distilled water.
IsotypeName :
IgG
Gene :
SPN / CD43
StandardGeneSymbol :
SPN
Reactivity :
Mouse, Rat, Human
Usage :
IHC, IHC-P (0.5 - 1 µg/ml), WB (0.5 - 1 µg/ml)
ShortWebDescription :
CD43 antibody LS-C357769 is an unconjugated rabbit polyclonal antibody to CD43 (SPN) from human. It is reactive with human, mouse and rat. Validated for IHC and WB.
UsageText :
CD43, also known as leukosialin or sialophorin, is a transmembrane cell surface protein that in humans is encoded by the SPN gene. It is mapped to 16p11.2. It is a major sialoglycoprotein on the surface of human T lymphocytes, monocytes, granulocytes, and some B lymphocytes, which is important for immune function and may be part of a physiologic ligand-receptor complex involved in T-cell activation. Expression of CD43 is deficient and/or defective in the X-chromosome-linked immunodeficiency disorder Wiscott-Aldrich syndrome, suggesting that CD43 have a role in T-cell activation. T-cell activation requires the removal of CD43 from the immunologic synapse to allow efficient engagement of the TCR with molecules on the APC.
Synonyms :
SPN, GPL115, Leukosialin, Leukocyte sialoglycoprotein, Galactoglycoprotein, GALGP, Sialophorin, LSN, CD43, CD43 antigen
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.