This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CD34 Antibody (N-Terminus, clone QBEnd/10) LS-C357765
catalog :
LS-C357765
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
QBEND/10

The same clone is also sold as:
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
product information
AntibodyID :
369310
AntibodyName :
LS-C357765
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
CD34 Antibody (N-Terminus, clone QBEnd/10) LS-C357765
Specificity :
Human CD34
ClonalityDesc :
Monoclonal
CloneName :
QBEnd/10
AntibodyModification :
Unconjugated
AntigenModification :
N-Terminus
PresentationDesc :
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
ImmunogenDesc :
A detergent solubilized vesicular suspension prepared from human term placenta.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 2°C to 8°C.
IsotypeName :
IgG1,k
Gene :
CD34
StandardGeneSymbol :
CD34
Reactivity :
Human, Cynomolgus monkey, Rhesus monkey
NonReactiveSpecies :
Dog, Sheep, Bovine, Rat
Usage :
Flo (0.5 - 1 µg/10E6 cells), IF (0.5 - 1 µg/ml), IHC, IHC-P (0.5 - 1 µg/ml), IP, WB (0.25 - 0.5 µg/ml)
ShortWebDescription :
CD34 antibody LS-C357765 is an unconjugated mouse monoclonal antibody to CD34 (N-Terminus) from human. It is reactive with human, cynomolgus monkey and rhesus monkey. Validated for Flow, IF, IHC, IP and WB.
UsageText :
This antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. On the basis of differential sensitivity to degradation by specific enzymes, epitopes of monoclonal antibodies to CD34 are classified into three main categories, class I, class II and class III. This is a class II antibody whose epitope is resistant to neuraminidase but sensitive to glycoprotease and chymopapain. CD34 expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. CD34 antibody labels > 85% of angiosarcoma and Kaposi's sarcoma, but with a lower specificity.
Synonyms :
CD34, CD34 molecule, CD34 antigen, HPCA1
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.