This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
LifeSpan Biosciences
product type :
antibody
product name :
CD33 Antibody (clone C33/69) LS-C357761
catalog :
LS-C357761
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
C33/69

The same clone is also sold as:
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section
product information
AntibodyID :
369306
AntibodyName :
LS-C357761
TargetSpecies :
Human
Host Species :
Mouse
Product Name :
CD33 Antibody (clone C33/69) LS-C357761
Specificity :
Human CD33
ClonalityDesc :
Monoclonal
CloneName :
C33/69
AntibodyModification :
Unconjugated
PresentationDesc :
PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide
ImmunogenType :
Recombinant protein
ImmunogenDesc :
Recombinant human CD33 protein.
PurificationDesc :
Protein G purified
RecommendedStorageDesc :
Store at 2°C to 8°C.
IsotypeName :
IgG1,k
Gene :
CD33
StandardGeneSymbol :
CD33
gene family :
Immunoglobulin
Reactivity :
Human
Usage :
ELISA, Flo (0.5 - 1 µg/10E6 cells), IF (0.5 - 1 µg/ml), IHC, IHC-Fr (0.5 - 1 µg/ml), IP
ShortWebDescription :
CD33 antibody LS-C357761 is an unconjugated mouse monoclonal antibody to human CD33. Validated for ELISA, Flow, IF, IHC and IP.
UsageText :
This antibody recognizes a 67kDa glycoprotein, which is identified as CD33 (HLDA IV. WS Code M-505). CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies. these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells. ELISA: Order BSA-free format for coating.
Synonyms :
CD33, CD33 antigen, CD33 molecule, gp67, SIGLEC-3, p67, CD33 antigen (gp67), SIGLEC3
SalesRegion :
Worldwide
company information
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
CustomerSupport@lsbio.com
https://www.lsbio.com
1-206-464-1554
headquarters: USA
Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.